Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel...
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Here we report that epidermal keratinocytes in psoriatic lesions are characterized by activated Stat3. Transgenic mice with keratinocytes expressing a constitutively active Stat3 (K5.Stat3C mice) develop a skin phenotype either spontaneously, or in response to wounding, that closely resembles psoriasis. Keratinocytes from K5.Stat3C mice show upregu...
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Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
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TN_cdi_proquest_miscellaneous_67340058
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67340058
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1162
