Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer
Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer
About this item
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Author / Creator
Publisher
Dordrecht: Springer
Journal title
Language
English
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Publication information
Publisher
Dordrecht: Springer
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Scope and Contents
Contents
X-ray repair cross-complementing 1 (XRCC1) gene encodes for a scaffolding protein, which plays an important role in base excision DNA repair by bringing together DNA polymerase beta, DNA ligase III and poly(ADP-Ribose) polymerase (PARP) at the site of DNA damage. Three polymorphisms of the XRCC1 gene at codons 194, 280 and 399 leading to amino acid...
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Full title
Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer
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Record Identifier
TN_cdi_proquest_miscellaneous_67371385
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67371385
Other Identifiers
ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-004-1004-x
