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c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes

c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67401121

c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes

About this item

Full title

c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2005-02, Vol.24 (6), p.1075-1083

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Theileria
parasites infect and transform bovine lymphocytes, but host cell immortalization is reversible, as upon parasite death the lymphocytes rapidly die of apoptosis. Infection leads to a marked augmentation in the levels of lymphocyte c-Myc, and the parasite achieves this by inducing increased c
-myc
transcription and by prolonging th...

Alternative Titles

Full title

c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67401121

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67401121

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1208314

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