c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes
c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Theileria
parasites infect and transform bovine lymphocytes, but host cell immortalization is reversible, as upon parasite death the lymphocytes rapidly die of apoptosis. Infection leads to a marked augmentation in the levels of lymphocyte c-Myc, and the parasite achieves this by inducing increased c
-myc
transcription and by prolonging th...
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Full title
c-Myc activation by Theileria parasites promotes survival of infected B-lymphocytes
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TN_cdi_proquest_miscellaneous_67401121
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67401121
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1208314