Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection
Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection
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Full title
Author / Creator
Yi, John S , Du, Ming and Zajac, Allan J
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Understanding the factors that regulate the induction, quality, and longevity of antiviral T cell responses is essential for devising rational strategies to prevent or combat infections. In this study, we show that interleukin-21 (IL-21), likely produced by CD4⁺ T cells, directly influences the generation of polyfunctional CD8⁺ T cells and that the...
Alternative Titles
Full title
Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection
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Record Identifier
TN_cdi_proquest_miscellaneous_67407430
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67407430
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1175194
