IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection
IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection
About this item
Full title
Author / Creator
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Chronic viral infection is often associated with the dysfunction of virus-specific T cells. Our studies using Il21r-deficient (Il21r⁻/⁻) mice now suggest that interleukin-21 (IL-21) is critical for the long-term maintenance and functionality of CD8⁺ T cells and the control of chronic lymphocytic choriomeningitis virus infection in mice. Cell-autono...
Alternative Titles
Full title
IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67407441
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67407441
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1172815
