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Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67410871

Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

About this item

Full title

Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

Publisher

New York, NY: Am Thoracic Soc

Journal title

American journal of respiratory and critical care medicine, 2005-02, Vol.171 (4), p.305-314

Language

English

Formats

Publication information

Publisher

New York, NY: Am Thoracic Soc

More information

Scope and Contents

Contents

Chronic obstructive pulmonary disease is marked by alveolar enlargement and excess production of airway mucus. Acrolein, a component of cigarette smoke, increases mucin 5AC (MUC5AC), a prevalent airway mucin in NCI-H292 cells by transcriptional activation, but the signal transduction pathways involved in acrolein-induced MUC5AC expression are unkno...

Alternative Titles

Full title

Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67410871

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67410871

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.200408-1003OC

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