Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands
Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands
About this item
Full title
Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands
Author / Creator
Publisher
United States
Journal title
The Journal of nuclear medicine (1978), 2005-02, Vol.46 (2), p.326-334
Language
English
Formats
Publication information
Publisher
United States
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Scope and Contents
Contents
Our objective was to develop an array of alpha(7)-selective nicotinic cholinergic receptor (nAChR)-based imaging agents for PET and SPECT.
(2'R)-N-(11)C-Methyl-N-(phenylmethyl)-spiro[1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridin]-5'-amine 1 was synthesized by reaction of the corresponding desmethyl precursor with (11)C-CO(2) and reducti...
Alternative Titles
Full title
Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_67411896
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67411896
Other Identifiers
ISSN
0161-5505
