Acquired mutations in TET2 are common in myelodysplastic syndromes
Acquired mutations in TET2 are common in myelodysplastic syndromes
About this item
Full title
Author / Creator
Langemeijer, Saskia M C , Kuiper, Roland P , Berends, Marieke , Knops, Ruth , Aslanyan, Mariam G , Massop, Marion , Stevens-Linders, Ellen , van Hoogen, Patricia , van Kessel, Ad Geurts , Raymakers, Reinier A P , Kamping, Eveline J , Verhoef, Gregor E , Verburgh, Estelle , Hagemeijer, Anne , Vandenberghe, Peter , de Witte, Theo , van der Reijden, Bert A and Jansen, Joop H
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Joop Jansen and colleagues show that myelodysplastic syndromes frequently harbor somatic mutations in
TET2
. Analysis of lineage markers suggests that
TET2
mutations are early events contributing to malignant transformation.
Myelodysplastic syndromes (MDS) represent a heterogeneous group of neoplastic hematopoietic disorders
1
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Alternative Titles
Full title
Acquired mutations in TET2 are common in myelodysplastic syndromes
Authors, Artists and Contributors
Author / Creator
Kuiper, Roland P
Berends, Marieke
Knops, Ruth
Aslanyan, Mariam G
Massop, Marion
Stevens-Linders, Ellen
van Hoogen, Patricia
van Kessel, Ad Geurts
Raymakers, Reinier A P
Kamping, Eveline J
Verhoef, Gregor E
Verburgh, Estelle
Hagemeijer, Anne
Vandenberghe, Peter
de Witte, Theo
van der Reijden, Bert A
Jansen, Joop H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67418327
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67418327
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.391
