High Prevalence of Fatty Acid Synthase Expression in Colorectal Cancers in Middle Eastern Patients a...
High Prevalence of Fatty Acid Synthase Expression in Colorectal Cancers in Middle Eastern Patients and Its Potential Role as a Therapeutic Target
About this item
Full title
Author / Creator
Publisher
Basingstoke: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
Basingstoke: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Many human epithelial cancers, particularly those with a poor prognosis, express high levels of fatty acid synthase (FASN), a key metabolic enzyme linked to synthesis of membrane phospholipids in cancer cells. Overexpression of FASN is linked with activation of the phosphatidylinositol-3'-kinase (PI3 K)/AKT pathway. However, the role of FASN in col...
Alternative Titles
Full title
High Prevalence of Fatty Acid Synthase Expression in Colorectal Cancers in Middle Eastern Patients and Its Potential Role as a Therapeutic Target
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67443228
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67443228
Other Identifiers
ISSN
0002-9270
E-ISSN
1572-0241
DOI
10.1038/ajg.2009.230
