IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation
IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Major histocompatibility complex (MHC) class I molecules present peptides, produced through cytosolic proteasomal degradation of cellular proteins, to cytotoxic T lymphocytes. In dendritic cells, the peptides can also be derived from internalized antigens through a process known as cross-presentation. The cellular compartments involved in cross-pre...
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Full title
IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation
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TN_cdi_proquest_miscellaneous_67472804
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67472804
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1172845
