Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely hu...
Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
Background
Novel antibody‐based immunotherapeutic strategies exploit chimeric immune receptors (CIR), expressed on the surface of transduced human peripheral blood mononuclear cells (PBMC), to redirect potent non‐MHC‐dependent cytotoxicity to tumor cells expressing a tumor‐associated antigen. However, clinical application of the strategy has bee...
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Full title
Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor
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Record Identifier
TN_cdi_proquest_miscellaneous_67488265
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67488265
Other Identifiers
ISSN
1099-498X
E-ISSN
1521-2254
DOI
10.1002/jgm.647
