Blockade of inducible costimulator pathway to prevent acute rejection in rat liver transplantation
Blockade of inducible costimulator pathway to prevent acute rejection in rat liver transplantation
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New York, NY: Elsevier Inc
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Language
English
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New York, NY: Elsevier Inc
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Abstract Background The role of inducible costimulator (ICOS) in transplantation immunity remains unclear. Methods A Lewis-to-Brown–Norway (BN) rat liver transplant model was used to explore the effect of ICOS blockade by small interference RNA. Recipient survival rate, number of CD25/ICOS–positive cells, ICOS mRNA and protein levels, and interfero...
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Full title
Blockade of inducible costimulator pathway to prevent acute rejection in rat liver transplantation
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TN_cdi_proquest_miscellaneous_67514929
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67514929
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ISSN
0002-9610
E-ISSN
1879-1883
DOI
10.1016/j.amjsurg.2008.09.014
