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eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67523677

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

About this item

Full title

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

Publisher

United States

Journal title

Molecular therapy, 2005-04, Vol.11 (4), p.591-599

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

beta-Globin transgenes regulated by the locus control region (LCR) are dominantly silenced by linked bacterial reporter genes in transgenic mice. Enhanced green fluorescent protein (eGFP) from jellyfish is an alternative reporter used in retrovirus vectors to transfer LCRbeta-globin genes into bone marrow. We show here that the eGFP coding sequence...

Alternative Titles

Full title

eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67523677

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67523677

Other Identifiers

ISSN

1525-0016

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