Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the...
Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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piRNAs have been implicated in transposon silencing. Tudor domain–containing protein-1 (Tdrd1) is now shown to interact with the mouse Piwi ortholog Mili and be part of a complex that contains Mili-associated piRNAs. Interaction occurs through the N terminus of Mili, which is dimethylated, a modification that promotes Tdrd1 interaction. The Tdrd1 m...
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Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile
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TN_cdi_proquest_miscellaneous_67589625
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67589625
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1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.1615
