TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of a...
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
In vitro
studies suggest that the adaptor TANK is needed for the production of type 1 interferon. Using TANK-deficient mice, Akira and colleagues instead find that TANK negatively regulates Toll-like receptor and B cell antigen receptor signaling
in vivo
.
The intensity and duration of immune responses are controlled by many proteins th...
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Full title
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
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TN_cdi_proquest_miscellaneous_67593470
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67593470
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1771
