Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl–CoA by brain micro...
Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl–CoA by brain microsomal long-chain fatty acyl–CoA synthetases: relevance to bipolar disorder
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Publisher
Berlin: Springer
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Language
English
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Publisher
Berlin: Springer
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Contents
Several drugs used to treat bipolar disorder (lithium and carbamazepine), when administered chronically to rats, reduce the turnover of arachidonic acid, but not docosahexaenoic acid, in brain phospholipids by decreasing the activity of an arachidonic acid-selective phospholipase A(2). Although chronic valproic acid produces similar effects on brai...
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Full title
Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl–CoA by brain microsomal long-chain fatty acyl–CoA synthetases: relevance to bipolar disorder
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TN_cdi_proquest_miscellaneous_67593636
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67593636
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ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-005-0272-4
