The Ink4/Arf locus is a barrier for iPS cell reprogramming
The Ink4/Arf locus is a barrier for iPS cell reprogramming
About this item
Full title
The Ink4/Arf locus is a barrier for iPS cell reprogramming
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Nature (London), 2009-08, Vol.460 (7259), p.1136-1139
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
On iPS cells and p53: the Ink4/Arf barrier
The
Ink4
/
Arf
tumour suppressor locus encodes three potent tumour suppressors, namely p16
Ink4a
, p15
Ink4b
and p19
Arf
. Here Li
et al
. show that the locus is rate limiting for reprogramming, and its transient inhibition significantly improves the generation of iPS...
Alternative Titles
Full title
The Ink4/Arf locus is a barrier for iPS cell reprogramming
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67623089
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67623089
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08290
