Response of Glioblastomas to EGFR Kinase Inhibitors
Response of Glioblastomas to EGFR Kinase Inhibitors
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United States: Massachusetts Medical Society
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English
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United States: Massachusetts Medical Society
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To the Editor:
Mellinghoff et al. (Nov. 10 issue)
1
identified coexpression of epidermal growth factor receptor (EGFR) deletion mutant variant III (EGFRvIII) and the tumor-suppressor protein PTEN as a molecular signature in pretreatment glioblastoma tissue that predicts sensitivity to EGFR inhibitors. However, several tumors that were resp...
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Response of Glioblastomas to EGFR Kinase Inhibitors
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TN_cdi_proquest_miscellaneous_67623803
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67623803
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ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMc053459