Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress
Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Mice experiencing repeated aggression develop a long-lasting aversion to social contact, which can be normalized by chronic, but not acute, administration of antidepressant. Using viral-mediated, mesolimbic dopamine pathway-specific knockdown of brain-derived neurotrophic factor (BDNF), we showed that BDNF is required for the development of this ex...
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Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress
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TN_cdi_proquest_miscellaneous_67649344
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67649344
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1120972
