Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses
Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses
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Publisher
Oxford: Elsevier Ltd
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Language
English
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Publisher
Oxford: Elsevier Ltd
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Scope and Contents
Contents
Since antigen-persistence plays a role for induction of immunity, we investigated the in vivo pharmacokinetic of a naked DNA vaccine at the site of its action, i.e., in the lymph node. After direct intralymphatic injection, naked DNA vaccine degraded within a few hours. In correlation with the short persistence of the DNA vaccine we found that the...
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Full title
Critical role for DNA vaccination frequency in induction of antigen-specific cytotoxic responses
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TN_cdi_proquest_miscellaneous_67662361
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67662361
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2005.09.018
