Nicotine activates the chemosensory cation channel TRPA1
Nicotine activates the chemosensory cation channel TRPA1
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Topical application of nicotine, as used in nicotine replacement therapies, causes irritation of the mucosa and skin. This reaction had previously been attributed to the activation of nicotinic acetylcholine receptors in chemosensory neurons. However, the Talavera
et al
. now demonstrate that TRPA1 may be crucial for nicotine-induced irritati...
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Full title
Nicotine activates the chemosensory cation channel TRPA1
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TN_cdi_proquest_miscellaneous_67668295
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67668295
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2379
