uPA+/+-SCID Mouse with Humanized Liver as a Model for In Vivo Metabolism of Exogenous Steroids: Meth...
uPA+/+-SCID Mouse with Humanized Liver as a Model for In Vivo Metabolism of Exogenous Steroids: Methandienone as a Case Study
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Publisher
Washington, DC: Am Assoc Clin Chem
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Language
English
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Publisher
Washington, DC: Am Assoc Clin Chem
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Scope and Contents
Contents
Adequate detection of designer steroids in the urine of athletes is still a challenge in doping control analysis and requires knowledge of steroid metabolism. In this study we investigated whether uPA(+/+)-SCID mice carrying functional primary human hepatocytes in their liver would provide a suitable alternative small animal model for the investiga...
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Full title
uPA+/+-SCID Mouse with Humanized Liver as a Model for In Vivo Metabolism of Exogenous Steroids: Methandienone as a Case Study
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TN_cdi_proquest_miscellaneous_67673368
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67673368
Other Identifiers
ISSN
0009-9147
E-ISSN
1530-8561
DOI
10.1373/clinchem.2008.119396
