Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential...
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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BBF2H7, a transcription factor activated by ER stress, is shown to be essential for chondrogenesis. Mice lacking BBF2H7 show severe chondrodysplasia and null chondrocytes have defects in secreting cartilage matrix proteins. BBF2H7 induces the expression of Sec23a, which is required for ER to Golgi transport, and rescues the secretion of cartilage m...
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Full title
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis
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TN_cdi_proquest_miscellaneous_67677313
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67677313
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb1962
