An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progressi...
An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression
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Publisher
United States
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Language
English
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Publisher
United States
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Contents
Integrins regulate adhesion-dependent growth, survival and invasion of tumor cells. In particular, expression of integrin alpha(v)beta(3) is associated with progression of a variety of human tumors. Here we reveal a previously undescribed adhesion-independent role for integrin alpha(v)beta(3) in pancreatic cancer and other carcinomas. Specifically,...
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Full title
An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression
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TN_cdi_proquest_miscellaneous_67686731
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67686731
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E-ISSN
1546-170X
DOI
10.1038/nm.2009
