Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mecha...
Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism
About this item
Full title
Author / Creator
Gelebart, P , Zak, Z , Anand, M , Dien-Bard, J , Amin, H M and Lai, R
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Interleukin-21 (IL-21) has been recently shown to modulate the growth of specific types of B-cell neoplasm. Here, we studied the biological effects of IL-21 in mantle cell lymphoma (MCL). All MCL cell lines and tumors examined expressed the IL-21 receptor. Addition of recombinant IL-21 (rIL-21)
in vitro
effectively induced STAT1 activation an...
Alternative Titles
Full title
Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_67690346
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67690346
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2009.100
