Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradat...
Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation
About this item
Full title
Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation
Author / Creator
Publisher
United States
Journal title
Nature medicine, 2005-04, Vol.11 (4), p.434-439
Language
English
Formats
Publication information
Publisher
United States
Subjects
More information
Scope and Contents
Contents
Expression of somatostatin in the brain declines during aging in various mammals including apes and humans. A prominent decrease in this neuropeptide also represents a pathological characteristic of Alzheimer disease. Using in vitro and in vivo paradigms, we show that somatostatin regulates the metabolism of amyloid beta peptide (Abeta), the primar...
Alternative Titles
Full title
Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67713958
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67713958
Other Identifiers
ISSN
1078-8956
