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Human mesenchymal stem cells (hMSCs) expressing truncated soluble vascular endothelial growth factor...

Human mesenchymal stem cells (hMSCs) expressing truncated soluble vascular endothelial growth factor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67715728

Human mesenchymal stem cells (hMSCs) expressing truncated soluble vascular endothelial growth factor receptor (tsFlk-1) following lentiviral-mediated gene transfer inhibit growth of Burkitt's lymphoma in a murine model

About this item

Full title

Human mesenchymal stem cells (hMSCs) expressing truncated soluble vascular endothelial growth factor receptor (tsFlk-1) following lentiviral-mediated gene transfer inhibit growth of Burkitt's lymphoma in a murine model

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The journal of gene medicine, 2006-03, Vol.8 (3), p.253-264

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Background
Efficient gene transfer to bone marrow derived mesenchymal stem cells (MSC) would provide an important opportunity to express potent anticancer agents in the tumour microenvironment because of their contribution to the tumour stroma.
Methods
HIV‐based lentiviral vectors were pseudotyped with four different envelope proteins; amp...

Alternative Titles

Full title

Human mesenchymal stem cells (hMSCs) expressing truncated soluble vascular endothelial growth factor receptor (tsFlk-1) following lentiviral-mediated gene transfer inhibit growth of Burkitt's lymphoma in a murine model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67715728

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67715728

Other Identifiers

ISSN

1099-498X

E-ISSN

1521-2254

DOI

10.1002/jgm.840

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