Inhibition of the Src and Jak Kinases Protects against Lipopolysaccharide-induced Acute Lung Injury
Inhibition of the Src and Jak Kinases Protects against Lipopolysaccharide-induced Acute Lung Injury
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Publisher
New York, NY: Am Thoracic Soc
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Language
English
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Publisher
New York, NY: Am Thoracic Soc
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Contents
The cascade of cellular and molecular pathways mediating acute lung injury is complex and incompletely defined. Although the Src and Jak family of kinases is upregulated in LPS-induced murine lung injury, their role in the development of lung injury is unknown. Here we report that systemic inhibition of these kinases using specific small molecule i...
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Full title
Inhibition of the Src and Jak Kinases Protects against Lipopolysaccharide-induced Acute Lung Injury
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TN_cdi_proquest_miscellaneous_67716661
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67716661
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ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.200407-981OC