Enhanced antitumor activity of irofulven in combination with irinotecan in pediatric solid tumor xen...
Enhanced antitumor activity of irofulven in combination with irinotecan in pediatric solid tumor xenograft models
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Publisher
Berlin: Springer
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Language
English
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Publisher
Berlin: Springer
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Contents
Irofulven, a novel chemotherapeutic agent with a broad spectrum of activity, is effective against preclinical models of pediatric tumors. The cytotoxic activity of irofulven is augmented when combined with agents that interact with DNA topoisomerase I; however, none of the reported studies have used the protracted dosing schedule found to be active...
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Full title
Enhanced antitumor activity of irofulven in combination with irinotecan in pediatric solid tumor xenograft models
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TN_cdi_proquest_miscellaneous_67717078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67717078
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ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-004-0902-2
