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Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodyn...

Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodyn...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67717407

Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodynamics-based transfection

About this item

Full title

Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodynamics-based transfection

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The journal of gene medicine, 2006-03, Vol.8 (3), p.324-334

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Background
Rapid intravenous injection of a large volume of plasmid DNA (pDNA), i.e. a transfection procedure based on hydrodynamics, is known to be an efficient and liver‐specific method of in vivo gene delivery. However, the gene expression is transient.
Methods
We investigated the effect of addition of polyethylene glycol (PEG) to a sol...

Alternative Titles

Full title

Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodynamics-based transfection

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67717407

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67717407

Other Identifiers

ISSN

1099-498X

E-ISSN

1521-2254

DOI

10.1002/jgm.850

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