Employing epigenetics to augment the expression of therapeutic proteins in mammalian cells
Employing epigenetics to augment the expression of therapeutic proteins in mammalian cells
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Publisher
Oxford: Elsevier Ltd
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Language
English
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Publisher
Oxford: Elsevier Ltd
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Scope and Contents
Contents
Recombinant proteins form an increasingly large part of the portfolio of biopharmaceutical companies. Production of these often complex transgenic proteins is achieved predominantly in mammalian cell lines but the process is hampered by low yields and unstable expression. Some of these problems are caused by gene silencing at the level of chromatin...
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Full title
Employing epigenetics to augment the expression of therapeutic proteins in mammalian cells
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TN_cdi_proquest_miscellaneous_67722409
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67722409
Other Identifiers
ISSN
0167-7799
E-ISSN
1879-3096
DOI
10.1016/j.tibtech.2006.01.007
