Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemi...
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia
About this item
Full title
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia
Author / Creator
Publisher
England
Journal title
The EMBO journal, 2006-03, Vol.25 (5), p.1000-1008
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Notch signaling plays a critical role in T-cell differentiation and leukemogenesis. We previously demonstrated that, while pre-TCR is required for thymocytes proliferation and leukemogenesis, it is dispensable for thymocyte differentiation in Notch3-transgenic mice. Notch3-transgenic premalignant thymocytes and T lymphoma cells overexpress pTalpha/...
Alternative Titles
Full title
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67724475
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67724475
Other Identifiers
ISSN
0261-4189
