Pseudomonas aeruginosa Elastase Disables Proteinase-Activated Receptor 2 in Respiratory Epithelial C...
Pseudomonas aeruginosa Elastase Disables Proteinase-Activated Receptor 2 in Respiratory Epithelial Cells
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Publisher
United States: Am Thoracic Soc
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Language
English
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Publisher
United States: Am Thoracic Soc
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Scope and Contents
Contents
Pseudomonas aeruginosa, a major lung pathogen in cystic fibrosis (CF) patients, secretes an elastolytic metalloproteinase (EPa) contributing to bacterial pathogenicity. Proteinase-activated receptor 2 (PAR2), implicated in the pulmonary innate defense, is activated by the cleavage of its extracellular N-terminal domain, unmasking a new N-terminal s...
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Full title
Pseudomonas aeruginosa Elastase Disables Proteinase-Activated Receptor 2 in Respiratory Epithelial Cells
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Record Identifier
TN_cdi_proquest_miscellaneous_67746432
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67746432
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ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2004-0274OC