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Etiology-Specific Endothelin-1 Clearance in Human Precapillary Pulmonary Hypertension

Etiology-Specific Endothelin-1 Clearance in Human Precapillary Pulmonary Hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67746504

Etiology-Specific Endothelin-1 Clearance in Human Precapillary Pulmonary Hypertension

About this item

Full title

Etiology-Specific Endothelin-1 Clearance in Human Precapillary Pulmonary Hypertension

Publisher

Northbrook, IL: Elsevier Inc

Journal title

Chest, 2006-03, Vol.129 (3), p.689-695

Language

English

Formats

Publication information

Publisher

Northbrook, IL: Elsevier Inc

More information

Scope and Contents

Contents

Endothelin (ET)-1 is a mediator of vascular remodeling seen in human pulmonary hypertension (PH), and it is normally cleared via endothelial ET-B receptors. Increased levels of ET-1 are found in precapillary PH, partly from increased synthesis. We hypothesized that the endothelial dysfunction and vascular remodeling seen in human precapillary PH wo...

Alternative Titles

Full title

Etiology-Specific Endothelin-1 Clearance in Human Precapillary Pulmonary Hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67746504

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67746504

Other Identifiers

ISSN

0012-3692

E-ISSN

1931-3543

DOI

10.1378/chest.129.3.689

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