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Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growt...

Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growt...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67753411

Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer

About this item

Full title

Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2005-04, Vol.115 (4), p.978-985

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The mainstay in the management of invasive bladder cancer continues to be radical cystectomy. With regard to improvement of quality of life, however, therapies that preserve the bladder are desirable. We investigated the use of intravesical PLK-1 small interfering RNA (siRNA) against bladder cancer. Patients with bladder cancers expressing high lev...

Alternative Titles

Full title

Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67753411

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67753411

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI23043

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