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Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressin...

Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67768424

Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc protein

About this item

Full title

Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc protein

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2005-04, Vol.24 (18), p.2944-2953

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Burkitt's lymphomas (BL) are characterized by the constitutive expression of c-Myc protein. In total, 50–60% of all BL cells carry mutant c-Myc proteins. Using a mouse model of spontaneously immortalized pro-B-lymphocytes (Ba/F3), we have investigated genomic instability mediated by the conditional expression of either wild-type (WT) or deletion bo...

Alternative Titles

Full title

Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67768424

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67768424

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1208467

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