Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated b...
Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Telomerase represents a relevant target for cancer therapy. Molecules able to stabilize the G-quadruplex (G4), a structure adopted by the 3′-overhang of telomeres, are thought to inhibit telomerase by blocking its access to telomeres. We investigated the cellular effects of four new 2,6-pyridine-dicarboxamide derivatives displaying strong selectivi...
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Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands
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TN_cdi_proquest_miscellaneous_67769151
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67769151
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0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1208468