Nonbilayer phase of lipoplex–membrane mixture determines endosomal escape of genetic cargo and trans...
Nonbilayer phase of lipoplex–membrane mixture determines endosomal escape of genetic cargo and transfection efficiency
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Cationic lipids are widely used for gene delivery, and inclusion of dioleoylphosphatidylethanolamine (DOPE) as a helper lipid in cationic lipid–DNA formulations often promotes transfection efficacy. To investigate the significance of DOPE’s preference to adopt a hexagonal phase in the mechanism of transfection, the properties and transfection effic...
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Full title
Nonbilayer phase of lipoplex–membrane mixture determines endosomal escape of genetic cargo and transfection efficiency
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TN_cdi_proquest_miscellaneous_67778672
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67778672
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1016/j.ymthe.2004.12.018
