Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer
Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Carcinoma of the prostate is the most commonly diagnosed cancer in men. The current pharmacological treatment of choice for progressive androgen-dependent prostate cancer is the nonsteroidal antiandrogen, bicalutamide, either as monotherapy or with adjuvant castration or luteinizing hormone-releasing hormone superagonists to block the synthesis of...
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Full title
Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer
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TN_cdi_proquest_miscellaneous_67789187
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67789187
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0500381102