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Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer

Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67789187

Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer

About this item

Full title

Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2005-04, Vol.102 (17), p.6201-6206

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Carcinoma of the prostate is the most commonly diagnosed cancer in men. The current pharmacological treatment of choice for progressive androgen-dependent prostate cancer is the nonsteroidal antiandrogen, bicalutamide, either as monotherapy or with adjuvant castration or luteinizing hormone-releasing hormone superagonists to block the synthesis of...

Alternative Titles

Full title

Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67789187

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67789187

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0500381102

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