Leishmanization: Use of an old method for evaluation of candidate vaccines against leishmaniasis
Leishmanization: Use of an old method for evaluation of candidate vaccines against leishmaniasis
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Publisher
Oxford: Elsevier Ltd
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Language
English
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Publisher
Oxford: Elsevier Ltd
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Contents
To establish the safety and reproducibility of live challenge with
Leishmania major, a single frozen stabilate was used in two open, single-arm leishmanization (LZ) trials. A total of 42 inoculations in 28 male adult volunteers were followed until complete healing.
Lesions induced by LZ are as diverse as natural infection, but much milder. To...
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Full title
Leishmanization: Use of an old method for evaluation of candidate vaccines against leishmaniasis
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TN_cdi_proquest_miscellaneous_67817274
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67817274
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2005.02.015