High-throughput RNAi screening by time-lapse imaging of live human cells
High-throughput RNAi screening by time-lapse imaging of live human cells
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
RNA interference (RNAi) is a powerful tool to study gene function in cultured cells. Transfected cell microarrays in principle allow high-throughput phenotypic analysis after gene knockdown by microscopy. But bottlenecks in imaging and data analysis have limited such high-content screens to endpoint assays in fixed cells and determination of global...
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Full title
High-throughput RNAi screening by time-lapse imaging of live human cells
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TN_cdi_proquest_miscellaneous_67883855
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67883855
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth876
