Retinoid Signaling Determines Germ Cell Fate in Mice
Retinoid Signaling Determines Germ Cell Fate in Mice
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Germ cells in the mouse embryo can develop as oocytes or spermatogonia, depending on molecular cues that have not been identified. We found that retinoic acid, produced by mesonephroi of both sexes, causes germ cells in the ovary to enter meiosis and inititate oogenesis. Meiosis is retarded in the fetal testis by the action of the retinoid-degradin...
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Retinoid Signaling Determines Germ Cell Fate in Mice
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TN_cdi_proquest_miscellaneous_67915692
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67915692
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1125691
