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Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurre...

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurre...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67921036

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients

About this item

Full title

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients

Publisher

Dordrecht: Springer

Journal title

Breast cancer research and treatment, 2005-06, Vol.91 (3), p.249-258

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer

More information

Scope and Contents

Contents

Tamoxifen has been a mainstay of adjuvant therapy for breast cancer for many years. We sought to determine if genetic variability in the tamoxifen metabolic pathway influenced overall survival in breast cancer patients treated with tamoxifen. We examined functional polymorphisms in CYP2D6, the P450 catalyzing the formation of active tamoxifen metab...

Alternative Titles

Full title

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67921036

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67921036

Other Identifiers

ISSN

0167-6806

E-ISSN

1573-7217

DOI

10.1007/s10549-004-7751-x

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