Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurre...
Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
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Publisher
Dordrecht: Springer
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Language
English
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Publisher
Dordrecht: Springer
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Contents
Tamoxifen has been a mainstay of adjuvant therapy for breast cancer for many years. We sought to determine if genetic variability in the tamoxifen metabolic pathway influenced overall survival in breast cancer patients treated with tamoxifen. We examined functional polymorphisms in CYP2D6, the P450 catalyzing the formation of active tamoxifen metab...
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Full title
Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
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TN_cdi_proquest_miscellaneous_67921036
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67921036
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ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-004-7751-x