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Differential roles for the coactivators CBP and p300 on TCF/β-catenin-mediated survivin gene express...

Differential roles for the coactivators CBP and p300 on TCF/β-catenin-mediated survivin gene express...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67928340

Differential roles for the coactivators CBP and p300 on TCF/β-catenin-mediated survivin gene expression

About this item

Full title

Differential roles for the coactivators CBP and p300 on TCF/β-catenin-mediated survivin gene expression

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2005-05, Vol.24 (22), p.3619-3631

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The inhibitor of apoptosis (IAP) protein survivin is highly expressed in cancers, but not in normal differentiated tissues. TCF/
β
-catenin signaling has been reported to participate in the regulation of
survivin
transcription in colon cancer. We have recently characterized ICG-001, a small molecule specific inhibitor of the
β
-ca...

Alternative Titles

Full title

Differential roles for the coactivators CBP and p300 on TCF/β-catenin-mediated survivin gene expression

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67928340

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67928340

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1208433

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