B Cell Ligand Discrimination Through a Spreading and Contraction Response
B Cell Ligand Discrimination Through a Spreading and Contraction Response
About this item
Full title
Author / Creator
Fleire, S.J , Goldman, J.P , Carrasco, Y.R , Weber, M , Bray, D and Batista, F.D
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
B cells recognize foreign antigens by virtue of cell surface immunoglobulin receptors and are most effectively activated by membrane-bound ligands. Here, we show that in the early stages of this process, B cells exhibit a two-phase response in which they first spread over the antigen-bearing membrane and then contract, thereby collecting bound anti...
Alternative Titles
Full title
B Cell Ligand Discrimination Through a Spreading and Contraction Response
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67935961
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67935961
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1123940
