Requirement for Notch1 signals at sequential early stages of intrathymic T cell development
Requirement for Notch1 signals at sequential early stages of intrathymic T cell development
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
Signaling through the transmembrane Notch1 receptor directs thymus-seeding progenitors (TSPs) to suppress their B cell potential and 'choose' the T cell fate. Present paradigms suggest that TSPs are contained in the multipotent early T lineage precursor (ETP) subset of thymocytes. However, we show here that the B cell potential of ETPs was not augm...
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Full title
Requirement for Notch1 signals at sequential early stages of intrathymic T cell development
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TN_cdi_proquest_miscellaneous_67958783
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67958783
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ISSN
1529-2908
E-ISSN
1529-2916,1365-2567
DOI
10.1038/ni1217
