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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T ce...

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67963048

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

About this item

Full title

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2006-05, Vol.441 (7090), p.235-238

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

On activation, T cells undergo distinct developmental pathways, attaining specialized properties and effector functions. T-helper (T
H
) cells are traditionally thought to differentiate into T
H
1 and T
H
2 cell subsets. T
H
1 cells are necessary to clear intracellular pathogens and T
H
2 cells are important for cleari...

Alternative Titles

Full title

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67963048

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67963048

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature04753

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