Preliminary evaluation of an in utero-lactation assay using 6-n-propyl-2-thiouracil
Preliminary evaluation of an in utero-lactation assay using 6-n-propyl-2-thiouracil
About this item
Full title
Author / Creator
Publisher
Berlin: Springer
Journal title
Language
English
Formats
Publication information
Publisher
Berlin: Springer
Subjects
More information
Scope and Contents
Contents
In this preliminary study, the potential of an in utero-lactation assay to detect thyroid effectors was evaluated by treating three dams/group with 6-n-propyl-2-thiouracil (PTU), a known thyroid antagonist, by oral gavage at doses of 0, 0.0032, 0.016, 0.08 and 0.4 mg/kg/day during fetal organogenesis and lactation. Hearing disturbances and an eleva...
Alternative Titles
Full title
Preliminary evaluation of an in utero-lactation assay using 6-n-propyl-2-thiouracil
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_68066400
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68066400
Other Identifiers
ISSN
0340-5761
E-ISSN
1432-0738
DOI
10.1007/s00204-004-0641-5