A deafness mutation isolates a second role for the tectorial membrane in hearing
A deafness mutation isolates a second role for the tectorial membrane in hearing
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
α-tectorin (encoded by
Tecta
) is a component of the tectorial membrane, an extracellular matrix of the cochlea. In humans, the Y1870C missense mutation in
TECTA
causes a 50- to 80-dB hearing loss. In transgenic mice with the Y1870C mutation in
Tecta
, the tectorial membrane's matrix structure is disrupted, and its adhesion zone i...
Alternative Titles
Full title
A deafness mutation isolates a second role for the tectorial membrane in hearing
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TN_cdi_proquest_miscellaneous_68079750
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68079750
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1496
