CTL response compensation for the loss of an immunodominant class I‐restricted HSV‐1 determinant
CTL response compensation for the loss of an immunodominant class I‐restricted HSV‐1 determinant
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Publisher
United States: Nature Publishing Group
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Language
English
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Publisher
United States: Nature Publishing Group
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Contents
The T‐cell response to even complex pathogens is often focused on only a handful of immunodominant determinants. Such narrow responses provoke a selective pressure that can drive the emergence of CTL escape variants, raising the question of whether a broader response, targeting multiple non‐dominant peptides may be more beneficial. To examine the a...
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Full title
CTL response compensation for the loss of an immunodominant class I‐restricted HSV‐1 determinant
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TN_cdi_proquest_miscellaneous_68106254
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68106254
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ISSN
0818-9641
E-ISSN
1440-1711
DOI
10.1111/j.1440-1711.2006.01469.x